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Noten en esta noticia el reporte de la infección concomitante de  con
pleuroneumonía contagiosa porcina. Tal como se actualiza aquí, se reconoce
que la puede estar acompañada de otros agentes virales y bacterianos,
situación que se espera aún más cuando la enfermedad es endémica. 
Saludos, Maria Irian
Dra. María Irian Percedo Abreu DrC
Investigadora Titular
Dirección Salud y Producción Animal
Centro Nacional de Sanidad Agropecuaria (CENSA)
Mayabeque, CUBA
Tlfno: 047-849174
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Enviado el: miércoles, 30 de diciembre de 2015 19:40
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Asunto: PRO/AH/EDR> Classical swine fever & Actinobacillus pleuropneumoniae
- China: (SX) mixed infection
CLASSICAL SWINE FEVER & ACTINOBACILLUS PLEUROPNEUMONIAE - CHINA
(SHANXI) MIXED INFECTION
****************************************************************************
************
A ProMED-mail post
<http://www.promedmail.org>
ProMED-mail is a program of the
International Society for Infectious Diseases <http://www.isid.org>
Date: Wed 30 Dec 2015
Source: Shanxi Daily [Chinese, transl & summ Dan Silver, edited]
<http://epaper.sxrb.com/shtml/sxnmb/20151229/315979.shtml>
 
Disease Situation: Recently, on a pig farm in Fushan County [Linshen
Municipality in Shanxi Province] with 179 head of piglets of around 30 kg,
there appeared fever, shivers, cyanosis, and multiple deaths.
Treatment regimens for CSF and HPS infection were initially followed.
First, Radix Isatidis injections, Bupleurum injections, Sulfamonomethoxine
tablets, and cephalosporins were used with poor effects. Then, treatment
regimens for swine paratyphoid were followed, using mainly Florfenicol
injections. Results were still sub-optimal, with steady increases in illness
and death among pigs.
Diagnosis: Based on the disease situation, clinical symptoms, necropsy
findings, and laboratory testing, the final confirmed diagnosis was mixed
infection by Classical Swine Fever and porcine contagious pleuropneumonia.
In recent years, with the development of intensive hog raising and increased
hog density, plus [the use of] tightly closed hog sheds in winter, mixed
infection of the 2 diseases shows up frequently.
--
Communicated by:
ProMED-mail Rapporteur Dan Silver
[Classical swine fever (CSF, Hog cholera) is a highly infectious viral
disease of swine, an OIE-listed disease (previously designated a "List A"
disease), which is regarded as endemic in China. Its incidence in China has,
according to the annual OIE reports, undergone a significant decrease since
2010. CSF is often mixed with other viral, bacterial and other diseases,
such as enzootic pneumonia or mycoplasmal pneumonia (e.g., _Mycoplasma
hyopneumoniae_), Porcine reproductive and respiratory syndrome (PRRS),
porcine circovirus and porcine contagious pleuropneumonia (PCP), caused by
_Actinobacillus pleuropneumoniae_ (APP).
The latter, mentioned in the above Chinese media report, is an infectious
porcine respiratory-tract disease causing severe economic losses worldwide
in the swine industry. These marked economic losses are associated with
retardation in the growth of infected pigs. 
Different clinical forms may be observed, from peracute to subacute or
chronic. Clinical signs are characterized by respiratory dyspnea with nasal
and oral bloody discharges, affecting pigs from any age but mostly those
12-16 weeks old, with characteristic lesions which consist of a mostly
bilateral necrotic haemorrhagic pneumonia of the caudal lung lobes. The
causative agent is a non-sporulated, immobile, facultative aerobic,
haemolytic and fermentative, Gram-negative coccobacillary bacterium. 
15 different serotypes are recognized based on the capsular antigens.
Serotypes 1, 2, 5, 9 and 11 are considered virulent isolates, being
responsible for either acute or chronic outbreaks of PCP. The agent is
regarded endemic in all pig-raising countries and is not a reportable
disease. 
Some of the above information is derived from Gomez-Laguna, J., et al.,
Infection dynamics and acute phase response of an _Actinobacillus
pleuropneumoniae_ field isolate of moderate virulence in pigs. Vet.
Microbiol. (2014) <http://dx.doi.org/10.1016/j.vetmic.2014.08.015>. - Mod.AS
A HealthMap/ProMED-mail map can be accessed at:
<http://healthmap.org/promed/p/348>.]
[See Also:
2009
----
Undiagnosed disease, porcine - Philippines (05): (Mindanao), RFI
http://promedmail.org/post/20090313.1047
2006
----
Swine fever, classical - China (Beijing), mixed infection susp
http://promedmail.org/post/20061223.3592
2005
----
Classical swine fever - South Africa (04)
http://promedmail.org/post/20050901.2594
2002
----
Actinobacillus pleuropneumoniae - USA (MI): alert
http://promedmail.org/post/20020920.5364]

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