Detalles: | Creado en 30 Diciembre 2015 | Visitas: 318

-------- Forwarded Message --------

Subject: [redesastres-l] Classical swine fever & Actinobacillus pleuropneumoniae - China: (SX) mixed infection
Date: Wed, 30 Dec 2015 20:41:40 -0500
From: Esta dirección de correo electrónico está protegida contra spambots. Usted necesita tener Javascript activado para poder verla.
To: Esta dirección de correo electrónico está protegida contra spambots. Usted necesita tener Javascript activado para poder verla.


A ProMED-mail post
ProMED-mail is a program of the
International Society for Infectious Diseases
Date: Wed 30 Dec 2015
Source: Shanxi Daily [Chinese, transl & summ Dan Silver, edited]
Disease Situation: Recently, on a pig farm in Fushan County [Linshen
Municipality in Shanxi Province] with 179 head of piglets of around 30
kg, there appeared fever, shivers, cyanosis, and multiple deaths.
Treatment regimens for CSF and HPS infection were initially followed.
First, Radix Isatidis injections, Bupleurum injections,
Sulfamonomethoxine tablets, and cephalosporins were used with poor
effects. Then, treatment regimens for swine paratyphoid were followed,
using mainly Florfenicol injections. Results were still sub-optimal,
with steady increases in illness and death among pigs.
Diagnosis: Based on the disease situation, clinical symptoms, necropsy
findings, and laboratory testing, the final confirmed diagnosis was
mixed infection by Classical Swine Fever and porcine contagious
In recent years, with the development of intensive hog raising and
increased hog density, plus [the use of] tightly closed hog sheds in
winter, mixed infection of the 2 diseases shows up frequently.
Communicated by:
ProMED-mail Rapporteur Dan Silver
[Classical swine fever (CSF, Hog cholera) is a highly infectious viral
disease of swine, an OIE-listed disease (previously designated a "List
A" disease), which is regarded as endemic in China. Its incidence in
China has, according to the annual OIE reports, undergone a
significant decrease since 2010. CSF is often mixed with other viral,
bacterial and other diseases, such as enzootic pneumonia or
mycoplasmal pneumonia (e.g., _Mycoplasma hyopneumoniae_), Porcine
reproductive and respiratory syndrome (PRRS), porcine circovirus and
porcine contagious pleuropneumonia (PCP), caused by _Actinobacillus
pleuropneumoniae_ (APP).
The latter, mentioned in the above Chinese media report, is an
infectious porcine respiratory-tract disease causing severe economic
losses worldwide in the swine industry. These marked economic losses
are associated with retardation in the growth of infected pigs.
Different clinical forms may be observed, from peracute to subacute or
chronic. Clinical signs are characterized by respiratory dyspnea with
nasal and oral bloody discharges, affecting pigs from any age but
mostly those 12-16 weeks old, with characteristic lesions which
consist of a mostly bilateral necrotic haemorrhagic pneumonia of the
caudal lung lobes. The causative agent is a non-sporulated, immobile,
facultative aerobic, haemolytic and fermentative, Gram-negative
coccobacillary bacterium.
15 different serotypes are recognized based on the capsular antigens.
Serotypes 1, 2, 5, 9 and 11 are considered virulent isolates, being
responsible for either acute or chronic outbreaks of PCP. The agent is
regarded endemic in all pig-raising countries and is not a reportable
Some of the above information is derived from Gomez-Laguna, J., et
al., Infection dynamics and acute phase response of an _Actinobacillus
pleuropneumoniae_ field isolate of moderate virulence in pigs. Vet.
Microbiol. (2014) <>. -
A HealthMap/ProMED-mail map can be accessed at:
[See Also:
Undiagnosed disease, porcine - Philippines (05): (Mindanao), RFI
Swine fever, classical - China (Beijing), mixed infection susp
Classical swine fever - South Africa (04)
Actinobacillus pleuropneumoniae - USA (MI): alert]